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Anatomical illustration of a penis.

Topical creams for penile cancer

Topical creams are sometimes used to treat very early penile cancer. These medicated creams are applied directly to the skin to destroy cancer cells without surgery.

This chapter contains general information about penile cancer. It is not a substitute for professional medical advice or treatment. Always consult your doctor or healthcare provider for guidance on your individual medical situation.

Last updated: June 2026

Reviewed by (2026 update):

  • Dr. Oscar Brouwer (EAU Guidelines Panel on Penile Cancer)
  • Dr. Walter Cazzaniga (YAU Working Group on Penile & Testis Cancer)