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Illustration of a medical machine, featuring a main console with a digital display, control buttons, typically used for patient monitoring or diagnostic purposes.

Radiotherapy for localised penile cancer

Radiotherapy uses targeted radiation to destroy cancer cells in localised penile cancer. It’s a non-surgical option that can help preserve the penis and its function.

Radiation therapy is the use of high-energy x-rays to kill cancer cells. It can be directed at cancer from outside of the body (external beam radiotherapy) or from within the body (brachytherapy). Both types of radiotherapy can be used to treat penile cancer which is confined to the penis as an alternative to surgery.

Localised penile cancer means the cancer is still only in the penis and hasn’t spread to lymph nodes or other parts of the body, but it may be more developed (possibly stage 2 or even early stage 3).

This chapter contains general information about penile cancer. It is not a substitute for professional medical advice or treatment. Always consult your doctor or healthcare provider for guidance on your individual medical situation.

Last updated: June 2026

Reviewed by (2026 update):

  • Dr. Oscar Brouwer (EAU Guidelines Panel on Penile Cancer)
  • Dr. Walter Cazzaniga (YAU Working Group on Penile & Testis Cancer)