Medications for penile curvature

Medications are usually considered if the curve is still mild, if you aren’t able or don’t want to have surgery, or if you want to try treatment first. They may help with discomfort, but most cannot make the curve completely straight or stop the plaque from forming.

Medications can be given in different ways: taken by mouth, injected into the penis, or applied to the skin.

This chapter contains general information about the treatment of penile curvature. It is not a substitute for professional medical advice or treatment. Always consult your doctor or healthcare provider for guidance on your individual medical situation.

Last updated: June 2026

Reviewed by (2026 update): 

• Dr. Afonso Morgado (EAU Guidelines Panel on Sexual and Reproductive Health)